Stochastic simulation: From the Gillespie algorithm, to kinetic proofreading, to chemoreception

Event Dates: 

Thursday, October 4, 2018 - 6:00am

CTQM Seminar Type: 

  • Related Seminar Series

Speaker Name(s): 

Philip Nelson

Speaker Affiliation(s): 

University of Pennsylvania

Abstract, Event Details: 

Stochastic simulation can make the molecular processes of cellular control more vivid than the traditional differential-equation approach by generating typical system histories instead of just statistical measures such as the mean and variance of a population. After introducing Gillespie's stochastic simulation algorithm, I'll give three case studies, involving gene expression, error correction, and adaptation in chemotaxis.